STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REM1RRAD and GEM like GTPase 1. (300 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.844
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.767
AFDN
Afadin, adherens junction formation factor.
    
 
 0.763
GRB2
Growth factor receptor bound protein 2.
   
 0.760
NFS1
NFS1 cysteine desulfurase.
      
 0.743
ZHX2
Zinc fingers and homeoboxes 2.
   
 0.742
H3AJ45_LATCH
Uncharacterized protein.
    
 0.734
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.734
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.722
G3BP1
G3BP stress granule assembly factor 1.
    
 
 0.719
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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