STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXD12Homeobox D12. (268 aa)    
Predicted Functional Partners:
SALL1
Spalt like transcription factor 1.
   
 
 0.639
HAND2
Heart and neural crest derivatives expressed 2.
    
 
 0.633
SALL4
Spalt like transcription factor 4.
   
 
 0.493
IDH2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
      
 0.475
HOXA13
Homeobox A13b.
  
  
0.461
SALL2
Uncharacterized protein.
   
 
 0.449
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.441
IRX2
Iroquois homeobox 2.
    
 
 0.432
IRX5
Iroquois homeobox 5.
    
 
 0.432
GLIS3
GLIS family zinc finger 3.
    
 
 0.427
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.