STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)    
Predicted Functional Partners:
UBE2V2-2
Ubiquitin-conjugating enzyme E2 variant 2.
   
 0.978
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.978
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.952
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.938
LOC102347893
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
  
  
 
0.900
RPS27A
Ribosomal protein S27a.
   
 0.889
TRIP12
Thyroid hormone receptor interactor 12.
    
 0.873
RNF20
E3 ubiquitin protein ligase.
    
 0.843
RNF40
E3 ubiquitin protein ligase.
    
 0.843
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.822
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.