STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSG101Tumor susceptibility 101. (392 aa)    
Predicted Functional Partners:
VPS28
VPS28 subunit of ESCRT-I; Belongs to the VPS28 family.
   
 0.999
RPS27A
Ribosomal protein S27a.
    
 0.990
MVB12B
Multivesicular body subunit 12B.
    
 0.989
MVB12A
Multivesicular body subunit 12A.
    
 0.987
VPS37A
VPS37A subunit of ESCRT-I.
   
 0.978
H3B7E6_LATCH
Uncharacterized protein.
    
 0.970
HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 0.970
VPS36
Vacuolar protein sorting 36 homolog.
    
 0.960
VPS37C
VPS37 C-terminal domain-containing protein.
   
 0.954
PDCD6IP
Programmed cell death 6 interacting protein.
   
 0.950
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.