STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (338 aa)    
Predicted Functional Partners:
H3AH67_LATCH
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.935
AGXT
Serine--pyruvate aminotransferase.
   
 
 0.934
HAO1
Hydroxyacid oxidase 1.
   
 
 0.929
GOT2
Aspartate aminotransferase.
   
 0.925
HAO2
Hydroxyacid oxidase 2.
   
 
 0.919
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
   
 0.909
DAO
D-amino acid oxidase.
   
 
 0.830
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.818
GCLC
Glutamate-cysteine ligase catalytic subunit.
   
 0.739
ANKRD2
Ankyrin repeat domain 2.
 
 
   0.575
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.