node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACVR1C | LOC102356233 | ENSLACP00000009358 | ENSLACP00000022578 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.756 |
ACVR1C | LOC102358988 | ENSLACP00000009358 | ENSLACP00000022115 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Mothers against decapentaplegic homolog. | 0.555 |
ACVR1C | SMAD3 | ENSLACP00000009358 | ENSLACP00000011989 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Mothers against decapentaplegic homolog. | 0.961 |
ACVR1C | SMAD4 | ENSLACP00000009358 | ENSLACP00000009312 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | MH2 domain-containing protein. | 0.555 |
ACVR1C | SMAD7 | ENSLACP00000009358 | ENSLACP00000006551 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Mothers against decapentaplegic homolog. | 0.736 |
ACVR1C | TGFBR1 | ENSLACP00000009358 | ENSLACP00000008197 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.567 |
ACVR1C | TGFBR2 | ENSLACP00000009358 | ENSLACP00000004468 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.840 |
ACVR1C | ZFYVE16 | ENSLACP00000009358 | ENSLACP00000010262 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Zinc finger FYVE domain-containing protein. | 0.432 |
ACVR1C | ZFYVE9 | ENSLACP00000009358 | ENSLACP00000012726 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Zinc finger FYVE domain-containing protein. | 0.432 |
LOC102356233 | ACVR1C | ENSLACP00000022578 | ENSLACP00000009358 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.756 |
LOC102356233 | LOC102358988 | ENSLACP00000022578 | ENSLACP00000022115 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Mothers against decapentaplegic homolog. | 0.670 |
LOC102356233 | SMAD3 | ENSLACP00000022578 | ENSLACP00000011989 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Mothers against decapentaplegic homolog. | 0.972 |
LOC102356233 | SMAD4 | ENSLACP00000022578 | ENSLACP00000009312 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | MH2 domain-containing protein. | 0.756 |
LOC102356233 | SMAD7 | ENSLACP00000022578 | ENSLACP00000006551 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Mothers against decapentaplegic homolog. | 0.712 |
LOC102356233 | TGFBR1 | ENSLACP00000022578 | ENSLACP00000008197 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.976 |
LOC102356233 | TGFBR2 | ENSLACP00000022578 | ENSLACP00000004468 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.902 |
LOC102356233 | ZFYVE16 | ENSLACP00000022578 | ENSLACP00000010262 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Zinc finger FYVE domain-containing protein. | 0.550 |
LOC102356233 | ZFYVE9 | ENSLACP00000022578 | ENSLACP00000012726 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | Zinc finger FYVE domain-containing protein. | 0.550 |
LOC102358988 | ACVR1C | ENSLACP00000022115 | ENSLACP00000009358 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.555 |
LOC102358988 | LOC102356233 | ENSLACP00000022115 | ENSLACP00000022578 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.670 |