STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSPC1Paraspeckle component 1. (525 aa)    
Predicted Functional Partners:
GTF3C2
General transcription factor IIIC, polypeptide 2, beta.
   
 
 0.578
H2ZYM4_LATCH
Uncharacterized protein.
    
 
 0.576
M3XKG1_LATCH
Uncharacterized protein.
    
 
 0.576
IPO8
Importin 8.
      
 0.537
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.525
CTCF
CCCTC-binding factor.
   
 
 0.458
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 
 0.431
ALYREF
Aly/REF export factor.
   
 
 0.414
PTBP2
Polypyrimidine tract binding protein 2.
   
 
 0.412
SRMS
Tyrosine-protein kinase.
    
  0.400
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.