STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (593 aa)    
Predicted Functional Partners:
LOC102360885
Luteinizing hormone, beta polypeptide.
   
 0.789
GPHB5
Glycoprotein hormone subunit beta 5.
     
 0.726
GDF9
Growth differentiation factor 9.
   
  
 0.676
BMP15
Bone morphogenetic protein 15.
      
 0.661
CYP17A1
Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.
   
  
 0.637
AMH
Anti-Mullerian hormone.
   
  
 0.635
INHBB
Inhibin subunit beta B.
   
  
 0.635
FBXO11
F-box protein 11.
  
   
 0.614
H3AFX8_LATCH
Si:dkey-23i12.9.
     
 0.606
STAR
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
   
  
 0.601
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.