STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (183 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
    
 0.933
TSC1
TSC complex subunit 1.
   
 0.929
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.851
ITSN2
Intersectin 2.
    
 0.844
H3B8U3_LATCH
Serine/threonine-protein kinase TOR.
    
 0.813
MTOR
Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.
    
 0.813
MLST8
MTOR associated protein, LST8 homolog.
    
 0.789
RRAGB
Ras-related GTP binding A.
     
 0.740
H3AJ45_LATCH
Uncharacterized protein.
    
 0.734
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.734
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.