STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGPL1Sphingosine-1-phosphate lyase 1. (566 aa)    
Predicted Functional Partners:
SGPP2
Sphingosine-1-phosphate phosphatase 2.
    
 0.974
SPHK2
Sphingosine kinase 2.
   
 0.965
PLPP2
Phospholipid phosphatase 2.
    
 0.958
PLPP3
Phospholipid phosphatase 3.
    
 0.921
LOC102349675
Phosphatidic acid phosphatase type 2D.
    
 0.921
ABAT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.798
ALDH5A1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.769
SGPP1
Sphingosine-1-phosphate phosphatase 1.
    
 0.763
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
    
 
 0.704
SLC29A3
Solute carrier family 29 member 3.
      
 0.685
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.