STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAIPTRAF interacting protein. (461 aa)    
Predicted Functional Partners:
LRR1
Leucine rich repeat protein 1.
   
  
 0.718
NEIL3
Nei like DNA glycosylase 3.
   
  
 0.630
FANCD2
FA complementation group D2.
   
 
 0.612
TATDN3
TatD DNase domain containing 3.
      
 0.554
MBLAC1
Metallo-beta-lactamase domain containing 1.
      
 0.554
FBXO5
F-box protein 5.
   
  
 0.553
USP37
Ubiquitin specific peptidase 37; Belongs to the peptidase C19 family.
    
 
 0.550
SPRTN
SprT-like N-terminal domain.
      
 0.544
CDC45
Cell division cycle 45.
   
  
 0.543
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 
 0.506
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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