STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRX1Iroquois homeobox 1. (460 aa)    
Predicted Functional Partners:
DLX2
Distal-less homeobox 2.
    
 
 0.609
CSRP1
Cysteine and glycine rich protein 1.
   
  
 0.551
TRPS1
Transcriptional repressor GATA binding 1.
    
 
 0.535
TSHZ1
Teashirt zinc finger homeobox 1.
    
 0.532
DLX1
Distal-less homeobox 1.
   
 
 0.528
SRF
Serum response factor.
   
 
 0.520
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.437
SMYD1
SET and MYND domain containing 1.
    
 0.434
H3AMM4_LATCH
Homeobox domain-containing protein.
   
 
 0.433
HHEX
Hematopoietically expressed homeobox.
   
 
 0.433
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.