STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1077 aa)    
Predicted Functional Partners:
LOC102348007
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.988
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.988
CDC42
Cell division cycle 42.
   
 0.972
LOC102351732
Uncharacterized protein.
   
 0.970
RAC1
Rac family small GTPase 1.
   
 0.970
RAC3
Rac family small GTPase 3.
   
 0.970
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
0.966
GAB1
GRB2 associated binding protein 1.
    
 0.961
PDPK1
3-phosphoinositide dependent protein kinase 1.
   
 0.960
IRS4
Insulin receptor substrate 4.
   
 0.958
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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