STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAB1DAB adaptor protein 1. (484 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.978
RELN
Reelin.
    
 0.931
LRP8
LDL receptor related protein 8.
    
 0.832
LDLR
Low density lipoprotein receptor.
    
 0.832
VLDLR
Very low density lipoprotein receptor.
    
 0.832
APP
Amyloid beta precursor protein.
    
 
 0.774
H3AJ45_LATCH
Uncharacterized protein.
   
 0.739
ITSN1
Intersectin 1 (SH3 domain protein).
   
 0.739
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.728
CD2AP
CD2 associated protein.
    
 0.728
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.