GRK5 protein (Latimeria chalumnae) - STRING interaction network

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gene neighborhood

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Score

GRK5

G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)

Predicted Functional Partners:

H2ZZF8_LATCH

0.725

CXCR4

0.705

LOC102348280

0.692

LOC102348541

0.692

H3AGL7_LATCH

0.692

RHO

0.667

LOC102347432

0.667

SMO

0.650

GNG2

0.629

CDC42BPA

0.612

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42BPA	GRK5	ENSLACP00000010801	ENSLACP00000015356	CDC42 binding protein kinase alpha.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.612
CXCR4	GRK5	ENSLACP00000012801	ENSLACP00000015356	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.705
CXCR4	H3AGL7_LATCH	ENSLACP00000012801	ENSLACP00000008788	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.691
CXCR4	LOC102348280	ENSLACP00000012801	ENSLACP00000005451	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.668
CXCR4	LOC102348541	ENSLACP00000012801	ENSLACP00000006086	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.669
GNG2	GRK5	ENSLACP00000018370	ENSLACP00000015356	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.629
GNG2	LOC102347432	ENSLACP00000018370	ENSLACP00000018849	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Rhodopsin.	0.718
GNG2	RHO	ENSLACP00000018370	ENSLACP00000014823	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Rhodopsin.	0.718
GNG2	SMO	ENSLACP00000018370	ENSLACP00000002758	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.779
GRK5	CDC42BPA	ENSLACP00000015356	ENSLACP00000010801	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	CDC42 binding protein kinase alpha.	0.612
GRK5	CXCR4	ENSLACP00000015356	ENSLACP00000012801	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.705
GRK5	GNG2	ENSLACP00000015356	ENSLACP00000018370	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.629
GRK5	H2ZZF8_LATCH	ENSLACP00000015356	ENSLACP00000002779	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Recoverin 3.	0.725
GRK5	H3AGL7_LATCH	ENSLACP00000015356	ENSLACP00000008788	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.692
GRK5	LOC102347432	ENSLACP00000015356	ENSLACP00000018849	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Rhodopsin.	0.667
GRK5	LOC102348280	ENSLACP00000015356	ENSLACP00000005451	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.692
GRK5	LOC102348541	ENSLACP00000015356	ENSLACP00000006086	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.692
GRK5	RHO	ENSLACP00000015356	ENSLACP00000014823	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Rhodopsin.	0.667
GRK5	SMO	ENSLACP00000015356	ENSLACP00000002758	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.650
H2ZZF8_LATCH	GRK5	ENSLACP00000002779	ENSLACP00000015356	Recoverin 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.725