HPN protein (Latimeria chalumnae) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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Score

HPN

Hepsin; Belongs to the peptidase S1 family. (415 aa)

Predicted Functional Partners:

HGF

0.745

MST1

0.735

H2ZX70_LATCH

0.675

H3A3U7_LATCH

0.675

H3B780_LATCH

0.609

MET

0.572

M3XL62_LATCH

0.520

LOC102358409

0.457

WDR90

0.436

AMACR

0.414

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMACR	HPN	ENSLACP00000015341	ENSLACP00000015441	Alpha-methylacyl-CoA racemase.	Hepsin; Belongs to the peptidase S1 family.	0.414
H2ZX70_LATCH	HPN	ENSLACP00000001991	ENSLACP00000015441	Uncharacterized protein.	Hepsin; Belongs to the peptidase S1 family.	0.675
H2ZX70_LATCH	LOC102358409	ENSLACP00000001991	ENSLACP00000009670	Uncharacterized protein.	Uncharacterized protein.	0.675
H3A3U7_LATCH	HPN	ENSLACP00000004318	ENSLACP00000015441	Uncharacterized protein.	Hepsin; Belongs to the peptidase S1 family.	0.675
H3A3U7_LATCH	LOC102358409	ENSLACP00000004318	ENSLACP00000009670	Uncharacterized protein.	Uncharacterized protein.	0.675
H3B780_LATCH	HGF	ENSLACP00000017751	ENSLACP00000023353	Uncharacterized protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.886
H3B780_LATCH	HPN	ENSLACP00000017751	ENSLACP00000015441	Uncharacterized protein.	Hepsin; Belongs to the peptidase S1 family.	0.609
H3B780_LATCH	MST1	ENSLACP00000017751	ENSLACP00000022835	Uncharacterized protein.	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.767
HGF	H3B780_LATCH	ENSLACP00000023353	ENSLACP00000017751	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.886
HGF	HPN	ENSLACP00000023353	ENSLACP00000015441	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepsin; Belongs to the peptidase S1 family.	0.745
HGF	LOC102358409	ENSLACP00000023353	ENSLACP00000009670	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.436
HGF	M3XL62_LATCH	ENSLACP00000023353	ENSLACP00000023468	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Uncharacterized protein.	0.765
HGF	MET	ENSLACP00000023353	ENSLACP00000015263	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	MET proto-oncogene, receptor tyrosine kinase.	0.998
HGF	WDR90	ENSLACP00000023353	ENSLACP00000002441	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	WD repeat domain 90.	0.436
HPN	AMACR	ENSLACP00000015441	ENSLACP00000015341	Hepsin; Belongs to the peptidase S1 family.	Alpha-methylacyl-CoA racemase.	0.414
HPN	H2ZX70_LATCH	ENSLACP00000015441	ENSLACP00000001991	Hepsin; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.675
HPN	H3A3U7_LATCH	ENSLACP00000015441	ENSLACP00000004318	Hepsin; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.675
HPN	H3B780_LATCH	ENSLACP00000015441	ENSLACP00000017751	Hepsin; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.609
HPN	HGF	ENSLACP00000015441	ENSLACP00000023353	Hepsin; Belongs to the peptidase S1 family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.745
HPN	LOC102358409	ENSLACP00000015441	ENSLACP00000009670	Hepsin; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.457