STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP45Rho GTPase activating protein 45. (1026 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.623
POLR2E
RNA polymerase II subunit E.
      
 0.553
UBASH3A
Ubiquitin associated and SH3 domain containing A.
      
 0.443
ARHGAP1
Rho GTPase activating protein 1.
     
 0.437
LOC102351732
Uncharacterized protein.
   
 0.435
GRAP2
GRB2 related adaptor protein 2.
     
 0.435
RAC1
Rac family small GTPase 1.
   
 0.435
RAC3
Rac family small GTPase 3.
   
 0.435
RND3
Rho family GTPase 3.
    
 0.431
LOC102348524
Uncharacterized protein.
    
 0.431
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.