STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2480 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 
 0.700
PPP2R2A
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 
 0.670
PLEKHA2
Pleckstrin homology domain containing A2.
    
 0.668
RAPGEF6
Uncharacterized protein.
    
 0.635
CNTN1
Contactin 1.
    
 0.607
GAB1
GRB2 associated binding protein 1.
    
 0.604
TNS4
Tensin 4.
    
 
 0.582
HS3ST1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.573
KCNK1
Potassium channel subfamily K member.
      
 0.573
PSD2
Pleckstrin and Sec7 domain containing 2.
      
 0.573
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.