STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (2690 aa)    
Predicted Functional Partners:
PKD2
Polycystin 2, transient receptor potential cation channel.
      
 0.699
RP1L1
Uncharacterized protein.
   
  
 0.540
PKD1
Polycystin 1, transient receptor potential channel interacting.
      
 0.487
H3B277_LATCH
Uncharacterized protein.
      
 0.487
HNF1A
HNF1 homeobox A.
   
  
 0.481
NEK8
NIMA related kinase 8.
      
 0.465
IFT88
Intraflagellar transport 88.
     
 0.441
ELF3
E74 like ETS transcription factor 3.
      
 0.422
CBLB
Cbl proto-oncogene B.
    
 0.406
H3AWW7_LATCH
Uncharacterized protein.
    
 0.406
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.