STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S1PR4Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (384 aa)    
Predicted Functional Partners:
S1PR1
Sphingosine-1-phosphate receptor 1.
  
  
0.923
GABRB3
Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.760
CDO1
Cysteine dioxygenase.
      
 0.711
GNA12
G protein subunit alpha 12.
 
  
 0.546
NR1D1
Nuclear receptor subfamily 1 group D member 1.
      
 0.463
CRHR2
Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.
     
 0.416
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase.
      
 0.411
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.