STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB5Integrin beta; Belongs to the integrin beta chain family. (697 aa)    
Predicted Functional Partners:
ITGAV
Integrin_alpha2 domain-containing protein.
   
 0.991
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 0.944
VCL
Vinculin.
   
 0.930
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.909
ILK
Integrin linked kinase.
    
 0.885
ITGA3
Integrin subunit alpha 3; Belongs to the integrin alpha chain family.
   
 0.840
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
   
 0.837
TLN2
Talin 2.
   
 0.836
ITGA11
Integrin subunit alpha 11; Belongs to the integrin alpha chain family.
   
 0.832
TLN1
Talin 1.
   
 0.816
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.