STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APLFFHA_2 domain-containing protein. (416 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross complementing 5.
    
 
 0.969
XRCC6
X-ray repair cross complementing 6.
    
 
 0.939
H3AC16_LATCH
X-ray repair complementing defective repair in Chinese hamster cells 1.
    
 
 0.932
CHFR
Checkpoint with forkhead and ring finger domains.
      
 0.891
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.827
LOC102360939
XRCC1_N domain-containing protein.
    
 
 0.789
LIG4
DNA ligase.
    
 
 0.786
PARP2
Poly [ADP-ribose] polymerase.
    
 
 0.775
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.767
TDP1
Tyrosyl-DNA phosphodiesterase 1.
    
 
 0.727
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.