STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F3E2F transcription factor 3. (340 aa)    
Predicted Functional Partners:
RB1
Uncharacterized protein.
   
 0.995
RBL2
RB transcriptional corepressor like 2.
   
 0.985
RBL1
RB transcriptional corepressor like 1.
   
 0.985
TFDP2
Transcription factor.
   
 0.982
TFDP1
Transcription factor.
   
 0.982
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.975
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.973
E2F1
E2F transcription factor 1.
  
 
0.973
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.960
E2F2
E2F transcription factor 2.
  
 
0.928
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.