STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF212Ring finger protein 212. (323 aa)    
Predicted Functional Partners:
SPO11
SPO11 initiator of meiotic double stranded breaks.
   
 
 0.773
MSH4
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 
 0.768
SYCE2
Synaptonemal complex central element protein 2.
      
 0.679
C14orf39
Chromosome 14 open reading frame 39.
      
 0.675
SYCP1
Synaptonemal complex protein 1.
      
 0.668
HSF2BP
Heat shock transcription factor 2 binding protein.
      
 0.640
HFM1
Helicase for meiosis 1.
      
 0.634
PSMA8
Proteasome subunit alpha type.
      
 0.623
TEX11
Testis expressed 11.
    
 
 0.566
SYCP3
Synaptonemal complex protein 3.
      
 0.555
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.