STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (487 aa)    
Predicted Functional Partners:
ACE2
Angiotensin-converting enzyme.
    
 
 0.776
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
   
 
 0.702
LOC102350038
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.572
H3ANL8_LATCH
Fibroblast activation protein, alpha; Belongs to the peptidase S9B family.
     
 0.563
H3A3Z8_LATCH
SERPIN domain-containing protein; Belongs to the serpin family.
    
 0.556
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.544
PRSS35
Serine protease; Belongs to the peptidase S1B family.
      
 0.540
LOC102360396
Si:dkey-26g8.5; Belongs to the peptidase C1 family.
 
   
 0.518
LOC102351388
Cathepsin L.1; Belongs to the peptidase C1 family.
 
   
 0.512
LOC102358477
Uncharacterized protein; Belongs to the peptidase C1 family.
 
   
 0.512
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.