STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KREMEN1Kringle containing transmembrane protein 1. (249 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
   
 0.999
LOC102358266
Dickkopf WNT signaling pathway inhibitor 1b.
    
 0.962
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.932
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.929
SLC25A42
Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 0.844
DKK4
Dickkopf WNT signaling pathway inhibitor 4.
    
 0.795
DKK2
Dickkopf WNT signaling pathway inhibitor 2.
    
 0.725
LOC102354118
Dickkopf_N domain-containing protein.
    
 0.725
CENPQ
Uncharacterized protein.
   
  0.704
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
      
 0.699
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.