STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPHK1Sphingosine kinase 1. (508 aa)    
Predicted Functional Partners:
UBE2O
Ubiquitin conjugating enzyme E2 O.
      
 0.701
RHBDF2
Rhomboid 5 homolog 2.
      
 0.692
SGPL1
Sphingosine-1-phosphate lyase 1.
 
 
 0.671
CCT5
Chaperonin containing TCP1 subunit 5.
    
  0.648
CCT7
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
    
  0.648
CCT4
T-complex protein 1 subunit delta.
    
  0.648
CCT6B
Chaperonin containing TCP1 subunit 6B.
    
  0.648
CCT2
Chaperonin containing TCP1 subunit 2.
    
  0.645
CCT3
T-complex protein 1 subunit gamma.
    
  0.632
CYGB
Cytoglobin; Belongs to the globin family.
      
 0.630
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.