STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL3Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (373 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.782
WDR90
WD repeat domain 90.
   
 0.617
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 0.616
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
  
 0.597
STOML1
Stomatin like 1.
  
 0.571
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
      
 0.556
LOC102354290
Uncharacterized protein.
   
 
 0.504
DCLK1
Doublecortin like kinase 1; Belongs to the protein kinase superfamily.
   
 0.491
PHB2
Prohibitin.
   
 0.480
LOC102349562
Prohibitin.
   
 0.480
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (22%) [HD]