STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP4Ubiquitin specific peptidase 4; Belongs to the peptidase C19 family. (915 aa)    
Predicted Functional Partners:
LOC102356738
USP domain-containing protein; Belongs to the peptidase C19 family.
 
     0.926
SART3
Spliceosome associated factor 3, U4/U6 recycling protein.
    
 
 0.901
USP1
Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family.
    
 
 0.722
UBA7
Uncharacterized protein; Belongs to the ubiquitin-activating E1 family.
   
 
 0.707
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.697
WWP2
E3 ubiquitin-protein ligase.
    
 0.659
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
 
 
    0.657
NEDD4L
E3 ubiquitin-protein ligase.
    
 0.656
TGFBR1
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.655
SMURF2
E3 ubiquitin-protein ligase.
    
 0.631
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.