STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1033 aa)    
Predicted Functional Partners:
BAZ1A
Bromodomain adjacent to zinc finger domain 1A.
    
 0.955
H4C11
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.936
CECR2
CECR2 histone acetyl-lysine reader.
    
 0.918
POLE3
Polymerase (DNA directed), epsilon 3 (p17 subunit).
    
 0.914
BPTF
Bromodomain PHD finger transcription factor.
   
 
 0.901
BAZ1B
Bromodomain adjacent to zinc finger domain 1B.
   
 0.901
RSF1
Remodeling and spacing factor 1.
   
 0.888
CHRAC1
Chromatin accessibility complex subunit 1.
    
 
 0.869
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 0.866
BAZ2B
Bromodomain adjacent to zinc finger domain 2B.
    
 0.787
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.