STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3BB04_LATCHSi:ch73-314g15.3. (319 aa)    
Predicted Functional Partners:
H4C11
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 
 0.673
TAF7
TATA-box binding protein associated factor 7.
    
 
 0.642
DMAP1
DNA methyltransferase 1 associated protein 1.
    
 
 0.588
H3AV84_LATCH
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 
 0.571
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
    
 
 0.566
H2AZ2
Histone H2A; Belongs to the histone H2A family.
    
 
 0.563
JMJD6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
    
 
 0.537
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 
 0.458
RUVBL2
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 
 0.455
CFDP1
Craniofacial development protein 1; May play a role during embryogenesis.
    
 
 0.438
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.