STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS3Suppressor of cytokine signaling 3. (205 aa)    
Predicted Functional Partners:
JAK1
Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.984
JAK2
Tyrosine-protein kinase.
   
 0.982
SOCS1
Suppressor of cytokine signaling 1a.
   
 
0.950
IRS2
Insulin receptor substrate 2.
    
 0.925
STAT3
Signal transducer and activator of transcription.
   
 0.922
IRS4
Insulin receptor substrate 4.
    
 0.911
IRS1
Insulin receptor substrate 1.
    
 0.911
LOC102360670
Uncharacterized protein.
  
  
 
0.903
CSF3R
Colony stimulating factor 3 receptor.
   
 0.860
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.839
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.