STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPHP1SH3 domain-containing protein. (561 aa)    
Predicted Functional Partners:
NPHP4
Nephrocystin 4.
   
 0.996
RPGRIP1L
RPGRIP1 like.
    
 0.967
TMEM67
Transmembrane protein 67.
   
  
 0.928
ITSN2
Intersectin 2.
     
 0.869
CEP290
Centrosomal protein 290.
   
 0.820
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.777
RPGR
Retinitis pigmentosa GTPase regulator.
    
 0.740
H3A0S5_LATCH
Uncharacterized protein.
    
 0.731
NPHP3
Nephronophthisis 3.
    
 0.725
MKS1
MKS transition zone complex subunit 1.
   
 
 0.710
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.