STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DGCR8DGCR8 microprocessor complex subunit. (771 aa)    
Predicted Functional Partners:
DROSHA
Drosha ribonuclease III.
   
 0.999
DICER1
Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.
   
 0.947
MRPL44
Mitochondrial ribosomal protein L44.
   
 0.899
XPO5
Exportin 5.
   
  
 0.857
MECP2
Methyl-CpG binding protein 2.
   
 0.762
DDX17
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
 
 0.757
DDX5
DEAD-box helicase 5; Belongs to the DEAD box helicase family.
    
 
 0.739
H2ZVK6_LATCH
Uncharacterized protein; Belongs to the argonaute family.
   
  
 0.714
METTL14
Methyltransferase like 14; Belongs to the MT-A70-like family.
   
  
 0.708
METTL3
Methyltransferase like 3; Belongs to the MT-A70-like family.
   
  
 0.703
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.