GPR61 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GPR61

G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family. (454 aa)

Predicted Functional Partners:

GPR139

0.627

GPR143

0.612

GPR39

0.599

GPR17

0.583

GPR3

0.567

TYR

0.473

SLC45A2

0.453

GPR142

0.411

GPER1

0.406

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPER1	GPR61	ENSLACP00000008155	ENSLACP00000019998	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.406
GPR139	GPR17	ENSLACP00000011016	ENSLACP00000018488	G protein-coupled receptor 139.	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	0.602
GPR139	GPR3	ENSLACP00000011016	ENSLACP00000022256	G protein-coupled receptor 139.	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.572
GPR139	GPR39	ENSLACP00000011016	ENSLACP00000004292	G protein-coupled receptor 139.	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	0.624
GPR139	GPR61	ENSLACP00000011016	ENSLACP00000019998	G protein-coupled receptor 139.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.627
GPR142	GPR61	ENSLACP00000019808	ENSLACP00000019998	G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.411
GPR143	GPR61	ENSLACP00000014610	ENSLACP00000019998	G protein-coupled receptor 143.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.612
GPR143	SLC45A2	ENSLACP00000014610	ENSLACP00000015816	G protein-coupled receptor 143.	Solute carrier family 45 member 2.	0.638
GPR143	TYR	ENSLACP00000014610	ENSLACP00000011256	G protein-coupled receptor 143.	Tyrosinase.	0.709
GPR17	GPR139	ENSLACP00000018488	ENSLACP00000011016	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 139.	0.602
GPR17	GPR3	ENSLACP00000018488	ENSLACP00000022256	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.546
GPR17	GPR39	ENSLACP00000018488	ENSLACP00000004292	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	0.552
GPR17	GPR61	ENSLACP00000018488	ENSLACP00000019998	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.583
GPR3	GPR139	ENSLACP00000022256	ENSLACP00000011016	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 139.	0.572
GPR3	GPR17	ENSLACP00000022256	ENSLACP00000018488	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	0.546
GPR3	GPR39	ENSLACP00000022256	ENSLACP00000004292	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	0.545
GPR3	GPR61	ENSLACP00000022256	ENSLACP00000019998	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.567
GPR39	GPR139	ENSLACP00000004292	ENSLACP00000011016	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 139.	0.624
GPR39	GPR17	ENSLACP00000004292	ENSLACP00000018488	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family.	0.552
GPR39	GPR3	ENSLACP00000004292	ENSLACP00000022256	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.545