STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM3BLysine demethylase 3B. (1770 aa)    
Predicted Functional Partners:
KDM2B
Uncharacterized protein.
   
 
 0.627
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
     
 0.568
JMJD6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
      
 0.559
KDM7A
Lysine demethylase 7A.
   
 
 0.557
KDM8
Lysine demethylase 8.
      
 0.545
JMJD4
Jumonji domain containing 4.
      
 0.535
KDM4A
Uncharacterized protein.
     
 0.516
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
    
 
 0.500
KMT2E
Lysine methyltransferase 2E.
   
  
 0.494
KDM4C
Uncharacterized protein.
     
 0.492
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.