STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISHCytokine inducible SH2 containing protein. (243 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.940
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.925
CUL2
Cullin 2; Belongs to the cullin family.
    
 0.780
H2ZXJ8_LATCH
Uncharacterized protein.
   
 0.753
RNF7
Ring finger protein 7.
   
 0.753
H3B5A0_LATCH
Fibronectin type-III domain-containing protein.
    
 
 0.672
COMMD1
Copper metabolism domain containing 1.
    
 0.637
ASB2
Ankyrin repeat and SOCS box containing 2.
     
 0.631
ASB1
Ankyrin repeat and SOCS box containing 1.
     
 0.614
NEDD8
NEDD8 ubiquitin like modifier.
     
 0.607
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.