RPAIN protein (Latimeria chalumnae) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

RPAIN

RPA interacting protein. (226 aa)

Predicted Functional Partners:

RPA1

0.562

RNASEH1

0.555

ANAPC16

0.544

FANCA

0.541

TELO2

0.468

H2ZWI5_LATCH

0.458

ELP5

0.450

RPA2

0.438

RIPK4

0.427

MIS12

0.426

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANAPC16	RPAIN	ENSLACP00000019885	ENSLACP00000020747	Anaphase promoting complex subunit 16.	RPA interacting protein.	0.544
ELP5	RPAIN	ENSLACP00000009403	ENSLACP00000020747	Uncharacterized protein.	RPA interacting protein.	0.450
FANCA	H2ZWI5_LATCH	ENSLACP00000013697	ENSLACP00000001756	FA complementation group A.	Uncharacterized protein.	0.709
FANCA	RPA1	ENSLACP00000013697	ENSLACP00000008142	FA complementation group A.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.976
FANCA	RPA2	ENSLACP00000013697	ENSLACP00000003064	FA complementation group A.	Replication protein A2.	0.627
FANCA	RPAIN	ENSLACP00000013697	ENSLACP00000020747	FA complementation group A.	RPA interacting protein.	0.541
H2ZWI5_LATCH	FANCA	ENSLACP00000001756	ENSLACP00000013697	Uncharacterized protein.	FA complementation group A.	0.709
H2ZWI5_LATCH	RNASEH1	ENSLACP00000001756	ENSLACP00000008022	Uncharacterized protein.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.749
H2ZWI5_LATCH	RPA1	ENSLACP00000001756	ENSLACP00000008142	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.999
H2ZWI5_LATCH	RPA2	ENSLACP00000001756	ENSLACP00000003064	Uncharacterized protein.	Replication protein A2.	0.997
H2ZWI5_LATCH	RPAIN	ENSLACP00000001756	ENSLACP00000020747	Uncharacterized protein.	RPA interacting protein.	0.458
H2ZWI5_LATCH	TELO2	ENSLACP00000001756	ENSLACP00000006639	Uncharacterized protein.	Telomere maintenance 2.	0.541
MIS12	RPAIN	ENSLACP00000020727	ENSLACP00000020747	MIS12 kinetochore complex component.	RPA interacting protein.	0.426
RIPK4	RPAIN	ENSLACP00000018007	ENSLACP00000020747	Receptor interacting serine/threonine kinase 4.	RPA interacting protein.	0.427
RNASEH1	H2ZWI5_LATCH	ENSLACP00000008022	ENSLACP00000001756	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Uncharacterized protein.	0.749
RNASEH1	RPA1	ENSLACP00000008022	ENSLACP00000008142	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.453
RNASEH1	RPAIN	ENSLACP00000008022	ENSLACP00000020747	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	RPA interacting protein.	0.555
RNASEH1	TELO2	ENSLACP00000008022	ENSLACP00000006639	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Telomere maintenance 2.	0.607
RPA1	FANCA	ENSLACP00000008142	ENSLACP00000013697	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	FA complementation group A.	0.976
RPA1	H2ZWI5_LATCH	ENSLACP00000008142	ENSLACP00000001756	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Uncharacterized protein.	0.999