STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED3Sprouty related EVH1 domain containing 3. (453 aa)    
Predicted Functional Partners:
NF1
Neurofibromin 1.
    
 0.751
NEK2
NIMA related kinase 2.
    
 0.720
PSMB3
Proteasome subunit beta 3.
   
 
  0.464
PSMB1
Proteasome subunit beta.
   
 
  0.463
PSMB2
Proteasome subunit beta.
   
 
  0.461
LOC102362556
Profilin; Belongs to the profilin family.
   
 0.459
PFN2
Profilin; Belongs to the profilin family.
   
 0.459
LOC102357963
Profilin; Belongs to the profilin family.
   
 0.459
PFN4
Profilin; Belongs to the profilin family.
   
 0.459
LIMD1
LIM domains containing 1.
    
 0.455
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.