STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RYR1Ryanodine receptor 1. (5024 aa)    
Predicted Functional Partners:
CASQ1
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
   
 0.961
CASQ2
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
   
 0.948
RYR3
Uncharacterized protein.
  
  
0.902
RYR2
Ryanodine receptor 2b (cardiac).
  
  
0.902
ASPH
Aspartate beta-hydroxylase.
   
 
 0.890
H3AEH3_LATCH
Asp-B-Hydro_N domain-containing protein.
   
 
 0.878
FKBP1B
Peptidylprolyl isomerase.
    
 0.804
FKBP1A
Peptidylprolyl isomerase.
    
 0.716
FKBP3
Peptidylprolyl isomerase.
    
 0.629
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
   
 
 0.521
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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