STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR77WD repeat domain 77. (322 aa)    
Predicted Functional Partners:
PRMT5
Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.
   
 0.999
CLNS1A
Chloride nucleotide-sensitive channel 1A.
   
 0.989
CPSF1
Cleavage and polyadenylation specific factor 1.
   
 0.974
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.974
SYMPK
Symplekin.
    
 0.974
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
    
 0.974
CSTF3
Cleavage stimulation factor subunit 3.
   
 0.961
FIP1L1
FIP1 like 1a (S. cerevisiae).
  
 0.956
H3AV94_LATCH
Fip1 domain-containing protein.
   
 0.947
RIOK1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
 
 0.938
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.