STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1272 aa)    
Predicted Functional Partners:
BUB3
BUB3 mitotic checkpoint protein.
   
 0.999
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 0.999
H3A0V9_LATCH
DUF5595 domain-containing protein.
   
 0.998
MAD1L1
Mitotic arrest deficient 1 like 1.
    
 0.998
CDC27
Cell division cycle 27.
    
 0.997
CDC23
Cell division cycle 23.
   
 0.996
NEK2
NIMA related kinase 2.
   
 0.994
ANAPC1
Anaphase promoting complex subunit 1.
   
 0.994
TTK
TTK protein kinase.
   
 
 0.994
CDC16
Cell division cycle 16.
   
 0.993
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.