STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (958 aa)    
Predicted Functional Partners:
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.974
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.957
EIF2S2
Eukaryotic translation initiation factor 2 subunit beta.
   
 
 0.820
EIF2S3
Eukaryotic translation initiation factor 2, subunit 3 gamma.
   
 
 0.813
ATF4
Activating transcription factor 4.
     
 0.724
H3B2C8_LATCH
Uncharacterized protein.
   
  
 0.712
ATF6
Activating transcription factor 6.
    
 
 0.704
ANKRD45
ANK_REP_REGION domain-containing protein.
   
 0.684
EEFSEC
Eukaryotic elongation factor, selenocysteine-tRNA specific.
   
 
 0.637
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
  
 0.610
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.