Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC102696298Histone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
LOC102699233
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.985
W5NLL5_LEPOC
Histone H2B; Belongs to the histone H2B family.
 
 
 0.958
W5MJK0_LEPOC
Histone H2B; Belongs to the histone H2B family.
 
 
 0.957
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.932
W5N7D6_LEPOC
Uncharacterized protein.
   
 0.932
W5MSQ6_LEPOC
AT rich interactive domain 4A (RBP1-like).
   
 0.892
W5NG20_LEPOC
Translocase of outer mitochondrial membrane 20.
   
 0.892
W5NAU2_LEPOC
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
 0.861
glyr1
Glyoxylate reductase 1 homolog (Arabidopsis).
    
 
 0.846
LOC102698545
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
   
 0.842
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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