STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itchE3 ubiquitin-protein ligase. (908 aa)    
Predicted Functional Partners:
cflar
CASP8 and FADD-like apoptosis regulator a; Belongs to the peptidase C14A family.
    
 0.972
rps27a
Ribosomal protein S27a.
    
 0.972
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.956
W5LYQ5_LEPOC
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.955
W5MWB1_LEPOC
E3 ubiquitin-protein ligase.
  
 
0.937
txnip
Thioredoxin interacting protein b.
    
 
 0.931
W5M5I9_LEPOC
E3 ubiquitin-protein ligase.
  
 
0.918
RNF11
Ring finger protein 11b.
    
 
 0.906
W5NH41_LEPOC
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.897
W5N0P5_LEPOC
Receptor protein-tyrosine kinase.
    
 0.889
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.