Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cxcr4Chemokine (C-X-C motif) receptor 4a; Belongs to the G-protein coupled receptor 1 family. (361 aa)    
Predicted Functional Partners:
cxcl12
Chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.999
ackr3
Atypical chemokine receptor 3b; Belongs to the G-protein coupled receptor 1 family.
    
 0.984
itch
E3 ubiquitin-protein ligase.
    
 
 0.971
LOC102692294
Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 
0.951
LOC102692498
Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 
0.951
gna12
Guanine nucleotide binding protein (G protein) alpha 12a.
    
 0.926
gna13
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.926
arrb1
Arrestin, beta 1.
    
 0.911
W5N6D1_LEPOC
Arrestin, beta 2a.
    
 0.911
LOC102690375
Adrenoceptor alpha 1Aa.
    
   0.827
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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