Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5LYD5_LEPOCE2F transcription factor 1. (431 aa)    
Predicted Functional Partners:
rb1
Retinoblastoma 1.
   
 0.999
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.996
W5MPI1_LEPOC
Cyclin A1; Belongs to the cyclin family.
   
 0.996
e2f3
E2F transcription factor 3.
  
 
0.992
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
    
 0.992
rbl2
Retinoblastoma-like 2 (p130).
   
 0.991
rbl1
Retinoblastoma-like 1 (p107).
   
 0.991
tfdp2
Transcription factor.
   
 0.991
tfdp1
Transcription factor.
   
 0.991
topbp1
DNA topoisomerase II binding protein 1.
    
 
 0.986
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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