Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5LYE8_LEPOCTransmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (255 aa)    
Predicted Functional Partners:
chmp3
Charged multivesicular body protein 3.
   
 0.957
snf8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
    
 0.953
ist1
IST1 factor associated with ESCRT-III.
   
 0.945
vps36
Vacuolar protein sorting 36 homolog.
    
 0.942
vps25
Vacuolar protein sorting 25 homolog.
    
 0.942
chmp2b
Charged multivesicular body protein 2Bb.
   
 0.933
chmp5
Charged multivesicular body protein 5a.
   
 0.933
vta1
Vesicle (multivesicular body) trafficking 1.
   
 0.930
W5NCW6_LEPOC
Charged multivesicular body protein 7.
    
 0.901
chmp6
Charged multivesicular body protein 6b.
   
 0.884
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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