Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5LYQ5_LEPOCTNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (548 aa)    
Predicted Functional Partners:
irak4
Interleukin 1 receptor associated kinase 4.
   
 0.999
ecsit
ECSIT signalling integrator.
    
 0.999
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.999
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.999
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
    
 0.999
sqstm1
Sequestosome 1.
    
 0.999
W5NBX6_LEPOC
Interleukin-1 receptor-associated kinase 1.
   
 0.999
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.999
W5M429_LEPOC
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.998
ube2n
Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.998
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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