Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
api5Apoptosis inhibitor 5. (529 aa)    
Predicted Functional Partners:
polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.969
tbc1d23
TBC1 domain family, member 23.
   
   0.932
ddx39a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa.
   
 
 0.871
ttc17
Tetratricopeptide repeat domain 17.
 
    
 0.828
mcm9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
    
   0.782
gphb5
Glycoprotein hormone subunit beta 5.
      
 0.738
glrx3
Glutaredoxin 3.
    
   0.691
osgep
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
    
   0.691
samm50
SAMM50 sorting and assembly machinery component.
 
    
 0.690
MAP2
Microtubule-associated protein.
    
   0.684
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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